No they cannot. They are not supposed to dissolve in your stomach which is why they are to be taken on an empty stomach to have any effect. If you cut them, it affects the coating on the pill. They do come in different doses however so hopefully you can find one that suits your needs.

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Supplements, SAMe (S-Adenosyl-L-Methionine) 400 mg, Nervous System Support*, 60 Tablets

Supplements, SAMe (S-Adenosyl-L-Methionine) 400 mg, Nervous System Support*, 60 Tablets

Q: I thought Sam-E needed to be in blister packs to preserve the pills themselves. I notice these are not. Is there a reason why?

The blister pack is one issue - I notice they recommend refrigerating these after opening which would help preserve.The more important point to me is that these have no mannitol (stomach upsetting) in themand that they are a true 400mg dose of SAM-e- not 400mg of the salt compound as many others are.

Q: What size are these pills? I have a hard time swallowing pills.

Long flat tablets, 7/8” X 3/8”, smooth coating, I find them easy to swallow. Don’t break them, they are enteric coated. Exposure to your stomach acids will significantly impact their effectiveness.

Q: Where where they made? good practices facility does not mean anything to me. they packed them in usa but where were they made? what country?

At NOW, our products are manufactured in the U.S. In regards to sourcing, our raw material sourcing is subject to change, so please contact us directly for information like country of origin. Anything we post here will later be inaccurate whenever we do make a change, so we are hesitant to post temporarily accurate information in a permanently accessible public forum. Our certified nutritionists can be reached at 888-669-3663 ext. 5 or productinfo@nowfoods.com.

Product ID: 5935185

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Details

Brand
NOW Foods
Flavor
Unflavored
Primary Supplement Type
multivitamin
Unit Count
60 Count
Item Form
Tablet
Item Weight
0.2 Pounds

✅GMP A-rated, third-party tested

💊400 mg potent dose

🧠Nervous system & emotional support

Frequently Bought Together

NOW Foods Supplements, SAMe (S-Adenosyl-L-Methionine) 400 mg, Nervous System Support*, 60 Tablets

NOW Foods Supplements, Methyl Folate 1,000 mcg, Metabolically Active Folate*, Co-Enzyme B Vitamin, 90 Tablets

NOW Foods Supplements, TMG Betaine (Trimethylglycine) 1,000 mg, Liver Support*, 100 Tablets

Description

💡 Elevate your mind and move freely—because feeling your best is non-negotiable!

BRAIN MOOD BOOST - Supports neurotransmitter balance for sharper focus and emotional well-being*
JOINT RELIEF POWER - Helps ease minor aches from daily strain, keeping you active and agile*
PURE CLEAN FORMULA - Free from dairy, gluten, soy, eggs, and sugar—perfect for clean living
HERITAGE YOU CAN TRUST - Crafted by a family-owned USA company since 1968, blending tradition with science
TRUSTED QUALITY ASSURANCE - GMP A-rated with ISO/IEC accredited lab testing ensures potency and purity

NOW Foods SAMe 400 mg delivers a clinically supported dose of S-Adenosyl-L-Methionine to promote nervous system health, emotional balance, and joint comfort. This clean-label supplement is rigorously tested under GMP A-rated standards and crafted in the USA by a trusted family-owned brand since 1968.

Have a Question? See What Others Asked

I thought Sam-E needed to be in blister packs to preserve the pills themselves. I notice these are not. Is there a reason why?

What size are these pills? I have a hard time swallowing pills.

Can these be cut?

Where where they made? good practices facility does not mean anything to me. they packed them in usa but where were they made? what country?

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