DAO Enzyme - Formerly Histamine Digest, DAO Enzyme Supplement for Histamine Food Intolerance, Supports Digestive Health, Upset Stomach (90 Capsules)*

If you don't produce DAO on your own (not too rare a condition, unfortunately), this enzyme helps a lot. (I found out from my Nutrition Genome test that I lack the genetics to produce my own DAO). My allergies (mold, dust, chicken, mango) were making me sick, and with each episode of reaction, my body couldn't metabolize all the histamine I'd made! So I'd just get sicker, now dealing with histamine overload. I know that there are people even more sensitive, who cannot eat certain histamine heavy foods. And this might help them as well. Check with a really good Functional Health expert. It was my wonderful San Mateo based chiropractor who told me about this supplement. It is NO WAY the cheapest DAO enzyme available, but it works! I reduced my allergic episodes from about 5 or 6 a year, to about 1 a year. And, I have to say, since I've been on this one (and I forget to take it every day), I was sick only once, and it lasted a mere 2 days instead of the usual debilitating 10. Love it.

Not to be dramatic, but this product has genuinely changed my quality of life. I’ve struggled with histamine reactions that made certain foods and drinks really difficult to enjoy. Before using this, foods that didn’t fit my FODMAP needs (like garlic, onions, spicy foods) and even a couple glasses of wine or a beer could leave me feeling awful the next day. I take two before having foods or drinks that I know can trigger symptoms, and the difference has been incredible. I’m able to enjoy meals out, socialize, and have a drink occasionally without the same level of reaction I used to experience. Being able to relax around food and enjoy these moments again has been such a gift. This has helped me feel like I can get back to living my life the way I used to.

This product is a real game changer. I've tried a lot of products like this and this one is the only one that has worked. Have a lot of food sensitivities and this helps me digest them. Also gives me a very significant burst of energy and muscle pump, not sure if that is a normal reaction but 10-15 min after I take it every time I get a huge rush of energy. Will subscribe to this forever. Thought it was expensive but easily worth it imo.

I think this DAO has been supportive. I’m not flaring after eating so perhaps it’s because I am taking one 10 min before the meal.

This is another you must have this product on hand. I have messed out activation. Take the pill pills 15 minutes before you eat otherwise I have severe heart palpitations every time I go to the ER they're always checking for heart trouble. I keep telling them it's from Cell but then I forget to take my pill. Do not forget to take your pill because anything you eat. You don't know if you're gonna get heart palpitations are not been using this company for ye been using this company for yearsars

I'm mean, it's not really a surprise given the fillers. Why shellac? I'm probably the most sensitive person alive due to a long standing chronic illness that has gradually brought my body to a place where I'm overwhelmed with histamine on a daily basis. I can only eat three foods and have been looking for answers for years. I finally figured out on my own (because docs seem clueless) that I have histamine intolerance and the reactions I have to foods fall exactly in line with having an over abundance of it. You can imagine how excited I was to try this product! I might actually get my life back. Nope. I started the way I always do with new supplements and opened the capsule to try only one of those tiny little beads you find inside. Five minutes later I'm reacting quite noticeably having all of my hallmark indications of a histamine reaction. Queasiness, itchiness, swelling sensation in throat among the most noticeable. Good thing I didn't take a whole pill. Since I know I've never been allergic to pork and the bottle says you don't even absorb the DAO in the first place I figure it must be a reaction to one of the fillers. The only ones I feel like I'm new to are the shallac crospovidone and carboxymethylcellulose. Seriously people, you want to help the ones who most desperately need this product and you use all this extra crap? I contacted Seeking Health customer service before I tried this product after reading the negative reviews to try and get some answers as to what might be causing the bad reactions and, of course, they could give me nothing but the generic "everyone reacts differently". Don't bother trying to get any real answers or speculation out of them or even a direction to follow where to find answers. So anyways, obviously I decided to take a chance with bad results. I even tried to break open one of the tiny balls to see if it would reveal the contents are separate and encapsulated in hopes that I could painstakingly weed out the actual DAO itself but it looks like it's all melted together...just in case anyone is as desperate as me to find a way to make it work XD. Unfortunately, I can only wait for a product to come out without all of the dangerous fillers as I've already whittled my diet down to three foods so the anti histamine diet is out for me. Seeking Health, don't bother to request I contact your customer service for help. I've done that and you didn't have a whole lot to offer so please just leave me alone until (or IF) you decide to figure out a way to offer us desperate people DAO without all extras our bodies can't handle. Thanks guys. Have a great day. Have fun eating whatever you want and enjoying life while I eat my Teff bread for the millionth time in my life and waste away in my bed. EDIT: For anyone who's interested. I've learned that you can essentially make your own DAO by growing pea sprouts and consuming them fresh and raw approx. after 10 days of germination. It's not hard to find out how to do this yourself online. I'm resorting to this. Feel free to ask for an update on this if you're curious. Today is 9/25/19 and my first batch won't be ready for a couple of weeks. UPDATE: For anyone who cares... I tested out a small amount of pea sprout and had the same reaction to it as I did this supplement SO, the only thing I can conclude is that it has something to do with my body's reaction to DAO itself. I can't think of a reason for why something that's supposed to lower histamine actually has the opposite reaction in my body. Symptoms were noticeable in my ease of breathing, throat swelling, nausea, dizziness and face tingling/itching. I did read a study on how the Catalase enzyme is supposed to help break down the byproducts of when histamine is broken down but since my reaction was so quick after hitting my stomach with both the peas and this supplement I'm not sure it has anything to do with a low level of Catalase in my body or anything like that. If I learn anything new I'll post it!

Taking this supplement has truly changed my life. I take it when I eat foods that I would normally react to due to having a histamine intolerance and my symptoms are basically negligible. Its not a cure for histamine intolerance, but it has done wonders for me with the side effects of consuming high histamine foods/drinks. The only downside to these are the price.... at $1/pill they're definitely not cheap, but if you have the money I wouldn't hesitate trying them out and see if they help with your symptoms.

I tried this as an alternative to Histame since it was supposedly stronger. Boy was I wrong! In addition to containing suspicious and unnecessary ingredients that I've reacted negatively to before, these pills failed to give relief from my high histamine symptoms. I'm glad it works for others. Since Histame is either discontinued or out of stock, I've just started taking Vitamin C (as ascorbic acid) to lower blood histamine levels. I use Nature's Way Buffered C-500. Vitamin C raises DAO and reduces blood histamine levels. There are clinical studies to prove it; just do your research. The only drawback is the potential for loose stools if you take too much ascorbic acid, so watch out for that. 1000 mg worked for me when I was having a histamine assault. If Vit. C doesn't work, try Amazing Herbs Nigella Sativa Oil (Black Seed Oil). It works when all others fail. Also, pea shoots/sprouts have DAO as well. I failed to grow my own pea shoots/sprouts at home, but a grocer had them. I just use a hand blender to create a green juice/smoothie. The pea sprouts aren't as effective as Histame, but they do add more DAO to my system. The Vitamin C has been a savior for me though. 2/1/17 update: I updated the review rating because it was my usage error that made it ineffective. Duh! You must take it exactly 15 minutes before eating the problem food to have a positive effect. Doing so did help, but I still don't like the weird ingredients. My apologies. I've found that acerola powder is a great source of vitamin C that doesn't cause loose stools at a high dosage. I buy the Mr. Ros brand and take from 2000 mg-4000 mg (4-8 tsp.) a day. I put the powder in water, add unrefined sugar, and it's a tasty juice. It's pricey at that dosage, so make the decision based on your own situation. I've also added white tea and holy basil tea to my weaponry against histamine intolerance. White tea is unfermented and has EGCG, which has been shown to block histamine. Holy basil is also good as a mast cell stabilizer. I drink two servings of the combo a day (1 tea bag of white tea w/2 tsp. of dried holy basil leaf per serving) in 8 oz. of hot water, steeped for 4 minutes. So far, so good.

Received in April. I used other product first, decided to give it a try today but the item was already open despite having a seal on the outside. I am not sure if the product has been tampered with and I’m concerned about purchasing anything else from this brand again.

Very good

Well done Amazon for supplying me with this product and at a good price!

Have struggled for years with histamine intolerance. After trying so many supplements this for me is the best to use when the meal has slightly higher levels of histamine than I would normally tolerate .

Good post considering it came from across the pond. Item was as described.