MotilPro, 180 Capsules

Okay this is a preliminary review. I just got it yesterday. I was able to take two capsules. One at one time of the day and one at the other. Between meals. Then I took one more in the evening. Because you want to take it on an empty stomach. It did not upset my stomach. I did hear my stomach moving all through the night. Off and on. Which to me was a good sign. Because usually I wake up in the morning and I'm just stuck. Like a brick. Then this morning I took two capsules, since the one three times yesterday didn't upset my stomach. You want to make sure you start slowly. But there's been so many great reviews. On this product. Course I have to see if it works for me personally, but so far even just hearing my stomach move last night. Funny thing to say, but it made me feel hopeful.

Great product, great vendor service.

First off, this product has ginger therefore some people will experience ginger burn. Those who have acid reflux are more prone to this. Drink a glass of water when you take it, and if you do struggle with acid reflux don’t lay down at least 30 minutes after taking. Just some tips I heard from a doctor on a podcast talking about pro kinetics. For more info on prokinetics, Dr. Allison Siebeker is a great choice! So I bought this and I started taking it and it seemed to do nothing for me. My RD put me on a protocol and my bowel movements were great. I thought it was the protocol, and these were doing nothing so I stopped taking them for about a week. Well that week I wasn’t having much luck with BMs, so I figured let me start taking this again. And the next day, my BMs were normal again! This worked for me. However, everyone’s body is different and there’s different prokinetics.

We've dealt with SIBO-induced constipation, leading to encopresis, leading to a flare and diagnosis of Crohn's. Miralax made things much worse (if you have SIBO, avoid it at all costs!). Magnesium works really well to soften the stool, but it doesn't do anything to move things out, so to speak. Mineral oil helped get things moving, but not enough. Senna based laxatives worked to some extent, but I was very concerned about long term use and possible cancer risk, and again, they did nothing to address the underlying cause of the problem (SIBO). We changed to a diet that supposedly works by reducing bad bacteria (SCD and/or combo of low FODMAP). The low FODMAP diet made things worse in the long run (over 2 years, it destroyed the good gut bacteria...you're supposedly only supposed to do it for 4-6 weeks, tops, but researchers didn't discover that until recently). SCD works really well, but again, it doesn't address the reduced motility that (at least in our case) likely caused the SIBO in the first place. Enter MotilPro. The 5-HTP works as a serotonin precursor (supposedly), which is similar to some of the pharmaceuticals that have been used for IBS over the years. The other stuff (mostly vitamins) helps speed things along. The ginger seems to work on some aspect of the motility receptors in the gut. Overall, this seems to really work! Unfortunately, it seems that, at therapeutic doses, it causes abdominal pain. If we do three pills (the recommended dose) it causes great motility, but pain. If we do two pills, the pain is less but I don't know if it works well enough. We tried it more than two weeks after finishing antibiotics the first time we dealt with SIBO, so it was likely too late in the game to make a difference. We're currently using it in conjunction with antibiotics this time around, so hoping there is some sort of synergistic effect and that we can drop off the dose as time goes on. Not sure. Our other options seem to be low dose naltrexone or erythromicin, per Dr. Siebecker's research (http://www.siboinfo.com/). Will update in a few months after things settle down a bit. Right now, I feel it's such a great product, hence the four stars, but in our case, the side-effects my trump the positives. Would give it a five star rating if the side effects were lower.

I learned about these when I was very sick with what I think was a bowel obstruction in 2017. The doctors gave me Linzess (horrible synthetic crap) to go, but I did research and came across these in my IBS type Facebook groups. I took three to start since I was not having a bowel movement on my own without an enema. I was sooooo relieved when these worked and I was having a bowel movement every morning when I took these at night. The veggie encapsulation is easy to take, you may get some ginger burps afterwards, but hey, I'll do anything to poo... these things got me going again along with natural calm at night, but honestly I think I'd poo without the natural calm and just taking these. If you cant poo daily and have IBS, you will not be sorry. I take one a day now and the bottle lasts me months. Totally worth the approximately $10 a month to poo. Yup!

I really WANTED and tried to like MotilPro prokinetic and stay with it to treat my SIBO and ensure my motility was on track, however, I was not able to tolerate it. And with testing on/off use I am sure it was a MotilPro reaction. I was, at times, taking it with Xifaxan and Neomycin, but at other times was taking it alone with no other medications to interfere with it. I took it for 4 weeks beginning with 1x / day, and slowly increasing to 2x, 3x per day over the four weeks. I took a dose before bed because I read that is the ideal time to take prokinetics before intestines do the middle of the night 'sweep'. I began to have symptoms during the night including: waking during night, dry *dry* mouth, gulping air down from the base of my neck, extreme thirst after drinking loads of water, trouble swallowing saliva, winded / out of breath, tossing/turning, sensation of my whole torso-body pulsing with my heartbeats, sensation of my heart working much harder than it should be - aware of my heart working rather than just being at peace and not being aware of it. I told my doctor and stopped taking it... I gave it a rest for 4 full days, and my body returned to a more normal feeling, I wasn't aware of my heartbeat and weird chest energy anymore. I returned to normal sleep patterns, normal breathing, swallowing, everything. Then I started it again slowly just 1x day on a Monday, and Tuesday. By Wednesday, I had to call in sick to work and sleep half the day. I was utterly exhausted, total body fatigue. I had trouble swallowing again, heart working harder again, hear my heartbeat in my ear when I'm sleeping, I wake up gasping for breath, I stopped breathing in my sleep on more than one occasion and was terrified - consciously willing my lungs to please start breathing, dry mouth, headache deep inside the back left quadrant of my brain, shallow fast breathing, yawning to get more air, bad exterior ear sensitivity pain laying in bed, energy felt off, felt like I'd been poisoned. My doctor and I agree I can't tolerate it and I've stopped taking it again. I'm not writing this to slam the product, and I take other pure encapsulation products fine, but as feedback to share with you that you MAY also have a poor reaction, and to be aware to tell your doctor if you do. You're not just taking a benign little ginger supplement. If I had to guess (which I do), I would say I have some problem with 5-HTP and you may want to do some reading on it first. I don't know if it caused Serotonin Syndrome in me or not, but I am wondering. If you google 5-HTP you'll find some cautionary statements about possible side effects. I wish someone had told me about that first and what to watch out for before I bought it, so I'm doing it now here in the hopes you'll also do your homework for your own health and safety. In hindsight, once it started bothering me, I should have completely stopped and not kept continuing to try to power through it and give it another chance.

This is a great, simple, safe product. I take 1 cap 30 mins before lunch and dinner, and it really helps with my gastroparesis. The ingredients are high quality, and its a very trusted brand. The pills are easy to swallow with no taste or smell. I would recommend starting with 1 cap twice a day and working up slowly if needed. The directions on the bottle are super helpful as well.

I really was hoping for positive results. Unfortunately, the only thing I have noticed is virtually instant ginger burn. I have had motility issues since my early teens. I'm now in my 50's with all kinds of malabsorption/SIBO and autoimmune issues. I understand that this won't solve all my problems instantly but I was hoping for something more apparent than just heartburn. I can't manage more than one capsule at a time. I can't say that I've had any negative side effects(or any effects) besides that. I will continue until the bottle is finished and update then. The capsules are easily swallowed and I do trust PE for quality. Many of the supplements I use are from PE. I don't know if the ginger is actually crucial to the formula but it would be nice to try it ginger-free at full dosage. What do you say Pure Encapsulations? If you make it, I'll take it!