Vetoquinol Zylkene Calming Support Supplement for Small Dogs and Cats, Helps Promote Relaxation and Reduce External Stress Factors, Daily Behavioral Support and Anxiety Relief for Dogs and Cats, 75mg

My kitty Goose is the only one of 4 indoor cats we have that has had a terrible problem of marking (he’s 10 this year and this began 2 years ago) in one room of the house. Same spot over and over, no amount of enzyme cleaner or cleaning of the area and direct spot cleaning has made him stop. I was at my wits end and didn’t know what other steps to take, before going to the vet (he has been cleared of any medical complications) for prescribed medication, I figured I’d give this a shot. I give him one pill in the morning mixed with a quarter of his squeezable treat and he has completely stopped, he is much calmer overall, and actually seems at peace now. There are no side affects aside from the first dose where he literally looked like he was stoned for about an hour lmfao that has since stopped, and he acts completely normal after his dose (for his weight is recommended two, I only give him one) and he doesn’t notice any taste or smell from it, he gets excited when I shake the bottle in the mornings to mix it for him! I highly recommend this product for people struggling with a cat who has high anxiety or marking issues! From a very relieved cat mom who was ready to throw in the towel.

My dog HATES fireworks! I didn't read on box that you give one day B4 and one day off so I gave her one in AM and then sprinkled on her good @ 4pm. She was very calm but not sedated. No panting and crawling all over me. Wish I had enough notice on FL thunderstorms so I could use for that too.

I find this good for calming. It’s hard to say if this alone is helping but I do see a difference. It helps if it’s taken daily rather than as needed. It’s expensive so taking off one star.

Great product just a little expensive

I have a small terrier with allergies and anxiety. For her to be happy, I have to manage both. This product does a good job of relaxing her, though it is not the only thing I use. I do notice when I stop using it she is antsier, so I have chosen to continue the product. But the price continues to increase from expensive to untenable. I looked around for alternatives.The active ingredient is called Alpha-Casozepine, according to the label. So, in looking for products with this, it turns out that Lactium is a trademarked version of this. It was difficult to find a product with this alone. Ultimately, I found a Swanson Antistress human product that contained only this as an active ingredient. There are other products that have this ingredient along with other things that I didn't want. I'll see how this new product works once I receive it.Interestingly, Calmkeen, a product that markets itself as similar, has hydrolyzed milk protein as the active ingredient, but it does does not have the actual Alpha-Casozepine. I bought it to alternate with Zylkene, but it simply does not work as well for my dog. And the price, which is significantly cheaper than Zylkene, has continued to rise likely because Zylkene's has. Anyway, if money is no option, then Zylkene is an effective product. If you don't want to continue to pay chronic price increases, you may need to look for an alternative.