Vetoquinol Zylkene Calming Support Supplement for Small Dogs and Cats, Helps Promote Relaxation and Reduce External Stress Factors, Daily Behavioral Support and Anxiety Relief for Dogs and Cats, 75mg

I have a 4-year-old Maine Coon with a sensory processing disorder. My big boy, Barnum, has trouble processing textures and noises. I have the only Maine Coon in America who HATES to be brushed no matter the brush or comb used. (We have 12.) Everyday noises — the doorbell, microwave alarm, TV volume — completely unhinge him and send him running for his life. Prozac helped to some degree, but it also flattened him emotionally and didn’t fully address the sensory overload. Since adding Zylkene alongside an reduced Prozac dose, the change has been remarkable. Barnum is calmer (no longer flinching when the duct work in the attic pops or the ice maker drops ice), more social, and genuinely enjoying life again. He seeks affection, engages in play, and even participates in brush sessions willingly (with freeze dried chicken incentives!). The difference is subtle but profound — his nervous system feels soothed, not sedated. I give him 1 capsule every morning. 2 made him sleep all day. Zylkene has balanced his sensory overload and allowed his personality and spirit to come back. He’s alert but regulated, playful but not anxious, and much more comfortable navigating the household and daily life. Any owner of a cat with anxiety or sensory issue should try Zylkene. Worth every penny!

We love these, they help calm our dog. Max has breathing difficulties and these help him relax and breath better

My experience comes from a cat shelter and, in recent years, working as a professional cat behavior consultant. It's hard to know with supplements if they really are effective, especially when they are used in conjunction with other behavior modification strategies. I can say that I used them with my cats for about a month as we were transitioning into our new home, and I thought they were helpful. I like that they have fewer potential side effects than prescription medication. Most cats don't mind the taste. For cats with more discerning taste, you can give the gel caps whole, on a lick mat in a pile of mixed-texture treats. The only drawback, from my perspective, is these supplements are pricey, which makes them less feasible for long-term use.

This is a NON-Drowsy supplement that truly does work! This calms my cat without making him sleepy so that I'm able to take him to the vet or give him needed medication. In addition, he is a hyper personality and sometimes is aggressive to our other cat & this supplement makes him less so. I like it that it doesn't change his personality or activity level but it does help him accept medication and vet visits.

I have a small terrier with allergies and anxiety. For her to be happy, I have to manage both. This product does a good job of relaxing her, though it is not the only thing I use. I do notice when I stop using it she is antsier, so I have chosen to continue the product. But the price continues to increase from expensive to untenable. I looked around for alternatives. The active ingredient is called Alpha-Casozepine, according to the label. So, in looking for products with this, it turns out that Lactium is a trademarked version of this. It was difficult to find a product with this alone. Ultimately, I found a Swanson Antistress human product that contained only this as an active ingredient. There are other products that have this ingredient along with other things that I didn't want. I'll see how this new product works once I receive it. Interestingly, Calmkeen, a product that markets itself as similar, has hydrolyzed milk protein as the active ingredient, but it does does not have the actual Alpha-Casozepine. I bought it to alternate with Zylkene, but it simply does not work as well for my dog. And the price, which is significantly cheaper than Zylkene, has continued to rise likely because Zylkene's has. Anyway, if money is no option, then Zylkene is an effective product. If you don't want to continue to pay chronic price increases, you may need to look for an alternative.