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🚿 Keep your pipes flowing like your life—clog-free and carefree!
Zep Drain Defense is a professional-strength, enzyme-based liquid formula designed to break down and prevent pipe build-up in sinks, tubs, garbage disposals, and more. Safe for PVC and septic systems, it offers up to 21 months of clog protection by naturally decomposing debris into harmless byproducts. Ideal for monthly maintenance, it delivers powerful, eco-friendly drain care without harsh chemicals or odors.























| ASIN | B001AZQR9C |
| Best Sellers Rank | #982 in Industrial & Scientific ( See Top 100 in Industrial & Scientific ) #6 in Commercial Drain Openers #19 in Chemical Drain Openers |
| Brand | Zep |
| Brand Name | Zep |
| Customer Reviews | 4.0 out of 5 stars 3,827 Reviews |
| Global Trade Identification Number | 00021709011302, 00021709600629, 20021709600623, 40021709600627 |
| Included Components | Concentrate |
| Item Form | bottle |
| Item Type Name | Zep Drain Defense Pipe Build-Up Remover - 64 Ounces - ZLDC648 - Professional Strength Liquid Pipe Build Up Remover,GREEN |
| Item Weight | 4.7 Pounds |
| Liquid Volume | 64 Fluid Ounces |
| Manufacturer | ZEP COMMERCIAL PRODUCTS |
| Model Number | ZLDC648 |
| Number of Items | 1 |
| Part Number | ZLDC648 |
| Product Benefits | Eliminates clogs, restores flow, and provides 21 months of drain protection |
| Scent | Unscented |
| State of Matter | Liquid |
| State of matter | Liquid |
| UPC | 021709600629 021709011302 |
| Unit Count | 64.0 Fluid Ounces |
| Warranty Description | Warranty |
P**A
Easy to use and does a fantastic job. HIGHLY RECOMMENDED.
This is the best product I have found for maintaining clean sink and shower drains. No need for harsh chemicals just to maintain clean pipes. I have not noticed a smell nor odor like harsh cleaning products have. Every few weeks, before taking a shower, I often pour the recommended amount down the shower/bath drain. I then use the toilet, shave, etc. It says to leave in for 15 minutes before flushing with warm water so I just plan accordingly. My shower drain was running very slowly so I started using this. After 4 times over a month period, everything was cleared and running smoothly. I now use it every few weeks to maintain the shower/bath drain. Container makes it easy to open and pour without any fuss or mess. Great value for the money. A fraction of the cost of some other brands but works just as well. I get the case of 8 to save on costs and so I make sure to have them on hand by each sink and shower/bath. I am extremely happy with this product. HIGHLY RECOMMENDED
J**Y
WORKS -- all that matters
Zep is my 'go to' for a clogged toilet. Might not work on first try ... or second ... even third ... BUT it eventually works and isn't as 'messy' or gross as using a snake. ~half bottle, 12 hour wait, HOT water chaser for 15 minutes ... flush *use when the house has multiple toilets because the clogged toilet will be unavailable **IF you need immediate results, use a snake or call a plumber
K**N
Seems to work ….
I use this once a week in our kitchen drain I make sourdough and discard daily . I try to make sure it does t go down the drain but into the trash . It has nice markings on the side for ease of use .
A**Y
I use this for my kitchen drain and also the drain for my central A/C unit.
This is a must have item in my house. I bought this after I had my kitchen drain unclogged. No problems since, but I also found that it works great in my A/C drain. No gunk buildup after 2 seasons (which is amazing in Florida), with just a capful in the air-handler drain once a month. A bottle lasts for many, many months. I will never be without a bottle.
K**Y
👎🏽
The worst product I ever used I used a whole bottle and I would not recommend it at all runaway pass it away pass it up. I returned it. I use the whole bottle and it didn’t even work at all. My wife bought a gel bottle of some other Drano stuff and it went down great this stuff is junk. I cannot believe that put their name on it.
R**M
More for preventive maintenance
Didn't clear my drain. Might be good for regular use to keep drain clear just not for bathrooms drains. Ended up ordering plumpers acid drain cleaner which did the job.
C**T
BAD REVIEWS, BECAUSE CUSTOMER NOT USEING CORRECTLY
THIS IS NOT A CLOG REMOVER..ITS ADDED TO YOUR SYSTEM FOR PIPES CLEANED OUT BULID UP OVER TIME.. IT HAS ENZYMES TO BREAK DOWN AND KEEPS PIPES CLEAN.. ITS A TREATMENT OVER TIME WORKS EXCELLLENT.. RUN OR ADD HOT WATER, THEN ADD TWO CUPS ,YES TWO CUPS,THEN ADD A ONE CUP OF HOT WATER..TO WASH OUT OF TRAP.. LET IN SET FOR AROUND 8 HOURS FOR BEST RESULTS.. DO ONCE A MONTH...
S**Y
Takes care of drain gnats!
Works well and doesn’t smell horrible like most other drain/pipe cleaners. Easy to use as well. We had issues with small drain gnats but this took care of that problem. We haven’t seen one since we started using this.
A**T
Saved me money on calling a plumber
I don’t usually write reviews, but after battling my kitchen sink for days, I feel like I just won a war. Plungers? Useless. Every other drain cleaner I could find? Nope. Even my auger failed me. I was this close to calling a plumber, but I figured I’d take one last shot with this product. And guess what? It actually worked! Took a few rounds—my clog was determined—but I could see progress each time, my sink slowly admitting defeat. Now that my pipes are back in working order, I’m not taking any chances and ordered another bottle for monthly maintenance cause there is no way in hell I'm going through all that again.
4**R
The best drain care liquid ever!
Take my word for it. You can't see the build up inside your drains and pipes. Don't use harsh chemicals. They will destroy you pipes. Use Zep. Monthly, regular usage of Zep will ensure that your pipes stay clog free. Eliminate costly visits from the plumber. Use Zep today!
U**N
works
This product does work but you need to use it as a maintenance product. My bathroom sink drain had next to no flow, but after six months of regular applications I have a clean drain. The toilet drain is not plugging as often and hopefully future applications will improve that. I do have a problem with Amazons pricing on this product and have used CT to cut the cost in half.
J**Y
It works
Good quality and great for my plastic pipes since it is not corrosive. It provided better results than Draino for my metal pipes as well.
M**.
Does not work
Did not work as advertised, waste of money.
Trustpilot
3 weeks ago
1 day ago