









🧬 Elevate your brain & heart health with science-backed methylation mastery!
Designs for Health Homocysteine Supreme delivers a potent, methylated B vitamin complex enhanced with L-serine and Trimethylglycine (TMG) to support efficient homocysteine metabolism. This vegetarian, non-GMO formula is clinically trusted by functional medicine professionals to promote optimal brain, heart, immune, and joint health through superior absorption and targeted methylation support.


















| ASIN | B00DJE2WP0 |
| Age Range Description | Adult |
| Allergen Information | Allergen-Free |
| Best Sellers Rank | #14,432 in Health ( See Top 100 in Health ) #1,701 in Multiple Vitamin-Mineral Combination Supplements |
| Brand | Designs for Health |
| Brand Name | Designs for Health |
| Customer Reviews | 4.7 out of 5 stars 958 Reviews |
| Diet Type | Vegetarian |
| Diet type | Vegetarian |
| Dosage Form | Capsule |
| Flavor | Unflavored |
| Flavour | Unflavored |
| Item Dimensions | 5.6 x 5.6 x 10.2 centimeters |
| Item Form | Capsule |
| Item Highlight | Methylated B Complex, B6, B12, Folate + L-Serine, TMG |
| Item Weight | 0.04 Ounces |
| Item form | Capsule |
| Manufacturer | Designs for Health |
| Manufacturer Part Number | HYS060-AZ |
| Material Type Free | en_AE |
| Number of Items | 1 |
| Primary Supplement Type | Methylation Support Capsules |
| Primary supplement type | Methylation Support Capsules |
| Product Benefits | metabolism_improvement, energy_management, antioxidant |
| Product benefits | metabolism_improvement, energy_management, antioxidant |
| Special Ingredients | B Vitamins, TMG, L-serine |
| Specific Uses For Product | Laboratory |
| Unit Count | 1.0 Count |
K**S
Significant Homocysteine reduction
This product works as it reduced my Homocysteine level like no other B vitamin supplement has done before. It does what it says on the label. I've been using this for two years, and my 6-monthly blood test results consistently show a significant difference. I don't plan to change what works.
T**N
Recomended
Been taking for awhile.. works!!!
J**R
This really works!
Fantastic product! My husband has had elevated homocysteine for several years. None of the other B complex vitamins he tried worked to lower it. His naturopathic doc recommended Homocysteine Supreme, and within 4 months taking 2 capsules daily his level went from 17 to 9. Highly recommend!
G**.
vitamin
It's a good vitamin
W**Y
Life / Brain Changer
I have tried 3 different products - I even tried “unmethylated” B12/folate etc. I do carry the MTHFR gene and have high homocysteine. THIS PRODUCT…. Not the others works for me. Though 2 caps is recommended and the dosage on the label is according to that - I can only do 1/4 of ONE capsule a day, but the difference in my life is night and day now. Im 67 and have lived most of my life with migraines, anxiety, depression and in the last couple of years I have been increasingly worried about my brain. My mother was diagnosed with Alzheimer’s at my age and I was mentally feeling worse and worse. I have recently come through a terrible tragedy - the violent death of my 40 year old son. After this happened I was significantly different in my brain. I could not shake the blackness (not just depression) I would wake in the morning and this horrible feeling was with me all day - consistently - over time. I put it down to grief. The first 3 days on this product I felt like I was 20 again. I remembered how I used to have hope and just feel “normal” like this. I realized quickly that I could not take 2 caps a day - I was literally flying mentally and did not sleep the first two nights. Over time I figured out my dosage and I am still in grief but I live every day ‘grounded’ and stable - I have energy and my brain fog is literally gone as is my black feeling in my brain. Anxiety and fear are just not there. I encourage everyone to at least get tested for the MTHFR gene and homocysteine - these tests are now available online without the need for a prescription (at least in California) - easy to find out! God bless you all - I am so thankful to the Lord for this answer to prayer.
Trustpilot
1 month ago
3 weeks ago