---
product_id: 4114433
title: "Plus Flea & Tick Spot Treatment for X-Large Breed Dogs 89-132 lbs. (Red) Count of 3"
brand: "frontline"
price: "49366CFA"
currency: XOF
in_stock: true
reviews_count: 9
category: "Frontline"
url: https://www.desertcart.sn/products/4114433-plus-flea-and-tick-spot-treatment-for-x-large-breed
store_origin: SN
region: Senegal
---

# 30-day continuous protection Waterproof formula Kills fleas, eggs, larvae & ticks Plus Flea & Tick Spot Treatment for X-Large Breed Dogs 89-132 lbs. (Red) Count of 3

**Brand:** frontline
**Price:** 49366CFA
**Availability:** ✅ In Stock

## Summary

> 🛡️ Stay ahead of pests — protect your XL companion with FRONTLINE Plus!

## Quick Answers

- **What is this?** Plus Flea & Tick Spot Treatment for X-Large Breed Dogs 89-132 lbs. (Red) Count of 3 by frontline
- **How much does it cost?** 49366CFA with free shipping
- **Is it available?** Yes, in stock and ready to ship
- **Where can I buy it?** [www.desertcart.sn](https://www.desertcart.sn/products/4114433-plus-flea-and-tick-spot-treatment-for-x-large-breed)

## Best For

- frontline enthusiasts

## Why This Product

- Trusted frontline brand quality
- Free international shipping included
- Worldwide delivery with tracking
- 15-day hassle-free returns

## Key Features

- • **Month-Long Shield:** One monthly dose delivers nonstop flea & tick defense for 30 days.
- • **Trusted for 20+ Years:** Veteran pet owners rely on FRONTLINE Plus for proven, consistent protection.
- • **Waterproof & Resilient:** Active ingredients stored in sebaceous glands keep working even after swims or baths.
- • **Complete Life Cycle Control:** Kills adult fleas, eggs, larvae, and ticks to break infestations before they start.
- • **Easy, Stress-Free Application:** Single-point topical treatment is quick, mess-free, and puppy-safe from 8 weeks old.

## Overview

FRONTLINE Plus Flea and Tick Treatment for X-Large Dogs (89-132 lbs) offers a fast-acting, waterproof topical solution that kills fleas, flea eggs, larvae, chewing lice, and ticks, including those that transmit Lyme disease. Trusted for over 20 years, its unique formula with fipronil and (S)-methoprene breaks the flea life cycle and provides continuous protection for a full 30 days with a single monthly application. Safe for puppies 8 weeks and older, this treatment deposits in the skin’s sebaceous glands to maintain efficacy even after water exposure, ensuring your large dog stays pest-free and comfortable.

## Description

Product Description Keep your dog protected with the number 1 name in flea & tick protection (1), FRONTLINE. FRONTLINE Plus for Dogs is a fast-acting, long-lasting waterproof flea & tick topical that's proven to kill fleas, flea eggs, flea larvae, chewing lice, and ticks that can transmit Lyme disease. Break the flea life cycle — FRONTLINE Plus for Dogs is specially formulated with fipronil and (S)-methoprene to kill existing adult fleas, flea eggs and flea larvae to guard against further infestations for flea control. Trusted by pet owners for over 20 years (2) — FRONTLINE Plus for Dogs can be used on puppies as young as eight weeks old, weighing 5 pounds or more, and is easy to apply. Applied to a single point on your pet, the flea and tick control treatment covers your dog's entire body and deposits in the sebaceous glands. These glands act as a reservoir, continuously replenishing the treatment onto your pet, working even if your dog gets wet. Just one dose of FRONTLINE Plus each month protects against fleas & ticks for a full 30 days. FRONTLINE Plus also comes in a formula designed for cats and kittens eight weeks of age and older, 1.5lbs. and over so you can protect the dogs or cats in your house from fleas and ticks with FRONTLINE Brand Products. Appropriately treat all pets in your household monthly to effectively control fleas and ticks and prevent the establishment of new flea infestations. Subscribe and save today to make it easier to keep your dogs or cats protected year-round and make sure you never run out of FRONTLINE Plus. Be sure to visit our brand store and follow us to stay up to date on new FRONTLINE products, features, tips and more. References: (1) BI Marketing Excellence Survey performed by Kynetec, November 2023. (2) 20 years of trust in killing fleas and ticks demonstrated by various studies in the past 20 years including a 2002 Pet Owner Brand Awareness and Attitude Tracking Study performed by Bruno and Ridgway Research Associates and the 2023 BrandSpark© American Trust Study where FRONTLINE Brand Products were voted most trusted for brand for flea & tick prevention. Brand Story By Frontline Plus

## Features

- Keep your dog protected from fleas & ticks all month long with FRONTLINE Plus for Dogs a fast-acting, waterproof flea & tick topical that's proven to kill fleas, flea eggs, flea larvae, chewing lice, and ticks that can transmit Lyme disease
- Break the flea life cycle with FRONTLINE Plus, specially formulated with fipronil and (S)-methoprene to kill existing adult fleas, flea eggs and flea larvae to guard against further infestations for flea control
- Trusted by pet owners for over 20 years, FRONTLINE Plus for Dogs can be used on puppies as young as eight weeks old, weighing 5 pounds or more, and is easy to apply with one monthly dose providing protection from fleas & ticks for a full 30 days
- FRONTLINE Plus also comes in a formula designed for cats and kittens eight weeks of age and older, 1.5lbs. and over, so you can protect the dogs or cats in your house from fleas and ticks with FRONTLINE Brand Products
- Treat all dogs or cats in your household monthly to effectively control fleas and ticks and prevent the establishment of new flea infestations
- Subscribe & save today to make it easier to keep your dogs or cats protected year-round and make sure you never run out of FRONTLINE Plus

## Technical Specifications

| Specification | Value |
|---------------|-------|
| ASIN | B0002J1FP8 |
| Active Ingredients | fipronil and (S)-methoprene |
| Age Range Description | All Life Stages |
| Allergen Information | Abalone Free |
| Best Sellers Rank | #871 in Pet Supplies ( See Top 100 in Pet Supplies ) #11 in Dog Flea Drops |
| Brand | Frontline |
| Brand Name | Frontline |
| Customer Reviews | 4.4 out of 5 stars 15,262 Reviews |
| Dog Breed Size | Large |
| Global Trade Identification Number | 00350604287308 |
| Included Components | Package includes 3 applicators |
| Item Form | Liquid |
| Item Type Name | Topical Red box |
| Item Volume | 302.4 Milliliters |
| Item Weight | 1.6 Ounces |
| Manufacturer | Boehringer Ingelheim Animal Health |
| Manufacturer Part Number | 72220 |
| Model Number | 72220 |
| Scent | Unscented |
| Scent Name | Unscented |
| Target Species | Dog |
| Unit Count | 1 Count |
| Volume | 302.4 Milliliters |
| Warranty Description | If you are not satisfied with FRONTLINE Plus for any reason, please contact the Boehringer-Ingelheim Animal Health Customer Care Team at: 1-800-660-1842 |

## Product Details

- **Active Ingredients:** fipronil and (S)-methoprene
- **Age Range (Description):** All Life Stages
- **Allergen Information:** Abalone Free
- **Brand:** Frontline
- **Dog Breed Size:** Large
- **Global Trade Identification Number:** 00350604287308
- **Item Form:** Liquid
- **Item Volume:** 302.4 Milliliters
- **Item Weight:** 1.6 Ounces
- **Scent:** Unscented

## Images

![Plus Flea & Tick Spot Treatment for X-Large Breed Dogs 89-132 lbs. (Red) Count of 3 - Image 1](https://m.media-amazon.com/images/I/71FiB6zP-3L.jpg)
![Plus Flea & Tick Spot Treatment for X-Large Breed Dogs 89-132 lbs. (Red) Count of 3 - Image 2](https://m.media-amazon.com/images/I/81HWNyMk9sL.jpg)
![Plus Flea & Tick Spot Treatment for X-Large Breed Dogs 89-132 lbs. (Red) Count of 3 - Image 3](https://m.media-amazon.com/images/I/814CcTxB26L.jpg)
![Plus Flea & Tick Spot Treatment for X-Large Breed Dogs 89-132 lbs. (Red) Count of 3 - Image 4](https://m.media-amazon.com/images/I/814n+7Kn+kL.jpg)
![Plus Flea & Tick Spot Treatment for X-Large Breed Dogs 89-132 lbs. (Red) Count of 3 - Image 5](https://m.media-amazon.com/images/I/81dlsY2VC9L.jpg)

## Available Options

This product comes in different **Size** options.

## Questions & Answers

**Q: Does this product have an EPA number on the box?**
A: Yes it does. It's 100% USA EPA Registered and legal for sale in the USA.

**Q: What are the active ingredients?**
A: Zoom in on box, switched from advantage appears to work well.

**Q: Does the product kill ticks throughout the dogs body and not just near the application site?**
A: Throughout the body.  Our dogs have not had ticks for years, although you do need to continue to check them.

**Q: Will this work for a dog that is 210 lbs**
A: I have a 200 lb Great Dane and works for him…the best is the chew that lasts 3 months…have to get from vet and very expensive

## Customer Reviews

### ⭐⭐⭐⭐⭐ Review
*by J***S on April 25, 2026*



### ⭐⭐⭐⭐⭐ Review
*by S***H on September 23, 2024*



### ⭐⭐⭐⭐⭐ Review
*by R***S on April 7, 2026*



## Frequently Bought Together

- Frontline Plus Flea and Tick Treatment for X-Large Dogs Up to 89 to 132 lbs. 3 Treatments
- Frontline Plus Flea and Tick Treatment for Large Dogs Up to 45 to 88 lbs. 3 Treatments
- Frontline Plus Flea and Tick Treatment for Small Dogs Upto 5 to 22 lbs. 3 Treatments

---

## Why Shop on Desertcart?

- 🛒 **Trusted by 1.3+ Million Shoppers** — Serving international shoppers since 2016
- 🌍 **Shop Globally** — Access 737+ million products across 21 categories
- 💰 **No Hidden Fees** — All customs, duties, and taxes included in the price
- 🔄 **15-Day Free Returns** — Hassle-free returns (30 days for PRO members)
- 🔒 **Secure Payments** — Trusted payment options with buyer protection
- ⭐ **TrustPilot Rated 4.5/5** — Based on 8,000+ happy customer reviews

**Shop now:** [https://www.desertcart.sn/products/4114433-plus-flea-and-tick-spot-treatment-for-x-large-breed](https://www.desertcart.sn/products/4114433-plus-flea-and-tick-spot-treatment-for-x-large-breed)

---

*Product available on Desertcart Senegal*
*Store origin: SN*
*Last updated: 2026-05-09*