- Plus Flea & Tick Spot Treatment for Large Breed Dogs 45-88 lbs. (Purple) Count of 3

I love using this for our Saint Benard/ Rough Collie mix, she is such a hairy dog and has had so many issues with fleas because of her long fur. It got so bad to the point she chewed all the hair off of her butt and tail. We tried so many different methods, even spraying our property to remove the fleas, changed foods because we couldn't understand how it was so bad still until we started using frontline. This product has made a huge difference for her. Within 2 weeks you started noticing a visible difference with her fur growing back and her finally being happy again it was a relief and I highly recommend to use this product.

So easy to use and seems to work as we have used multiple times and have found 0 fleas

This is a great product works well for my dog. He doesn’t have any issues with ticks or fleas since I’ve purchased. This would highly recommend.

Applied to dog 3 days ago and he is still scratching. Not sure about effectiveness on Florida fleas. No smell to speak of and no hair loss . He was a bit lethargic for the first day but went back to his old crazy self by day 2.

Way cheaper then at the vet’s office. I have used this product for my dogs for years with no issue.

After spending all kinds of money on, I put Frontline Plus on my Husky/Australian Cattle Dog mix after Next Guard II failed to work for him. Other than trying to rub it off (I kept him inside for 2 hours) he completely stopped scratching within 24 hours. He has a double coat of thick fur so rubbing it in real good to get it down to his skin was key. There were no adverse reactions at all. No smell. No odor. I highly recommend Frontline Plus Flea and Tick. May not work on every dog, but it exceeded my expectations on my dog.

The Frontline Plus flea and tick control for 45 to 88 pound dogs was worse than a disappointment. My dog is 50 pounds--well within the dosage range and become infested with fleas during the second month/dosage of usage. I'm not sure if the preventative actually worked the first month or if I just didn't notice the fleas until the fleas had multiplied enough for me to easily see them. I also don't know if I received the same quailty Frontline product through Amazon as a store/vet purchase. I have no reason to think that this was an imitation product other than some suspicions by other reviewers. Regardless, I had to use a flea dip and flea bomb my house. Once an infestation occurs, getting rid of the fleas is quite an aggravation. I'm trying Advantage II from PetSmart now to see if that will work. Hopefully, something will. June 24 2013, Advantage II didn't work either. I've had acceptable success from Certifect which I buy from my vet. I've used Certifect for over a year now. These flea and tick drops are made by Frontline but are only sold by prescription or thru a vetinarian. It works great for ticks. I've not had any problems with ticks from the first dosage. For a few days, though, after the dosage, he is a bit lethargic. However, my dog will still pick up fleas. The drops do kill the fleas but don't repel them quickly enough. Many people are having trouble with fleas because of the sucession of mild winters. The flea population isn't culled enough. During the summer months, the fleas just seem to overwhelm the medication and flea dips or additional organic sprays are necessary. I've been told that a new flea and tick pill may now be available. I know the flea pill works but I hadn't used it because I needed something for ticks. If this rumor is true, I'll definately give the pill a try. December 30, 2014. I finally found something that actually works for controlling fleas and ticks for my now 70 pound Labrador/mix. (He was a stray that my family adopted--short hair.) My vet introduced me to a new product (at the time) made by Bayer. It's a flea collar called Seresto that is sold on Amazon. I couldn't believe that a flea collar would really work. But, after having to hire Orkin to get the fleas out of my home, I was willing to try it. It's the best product that I have used for fleas and ticks. It's easy to use. I just put the collar on my dog. In few days all fleas were gone. The only ticks I ever find on my dog are the ones that he picks up during a walk or bush adventure. They are easily brushed off (when I notice them) and never attach. The collar lasts as long as advertised--8 months or in our case 5 months since he likes to swim. Unlike the drops, he is never lethargic afterwards. I have used several of these Seresto collars now and can't recommend them enough. They are sold on Amazon, by veterinarians, and I've seen them at Pet Smart as well.

While I KNOW it works on most dogs because I've used it before, it doesn't do the trick for a 140# Great Pyrenees. It seemed to work for the first few days, but it worked less than a month. Maybe it's because his hair is so long and thick; I don't know. My poor guy is scratching as if I never used it.

It works