PIASCLEDINE 90 CAPSULES, Piascledine is a product of herbal origin, with trophic effect in the connective tissue. It restores the normal cartilage structure by stimulating the synthesis of proteoglycans and collagen. Each capsule contains: Total extract of Persea gratissima/Glycine max unsaponifiable (Unsaponified fraction of Avocado oil 100 mg, Unsaponifiec fraction of Soybean oil 200 mg) ...................................... 300 mg Anhydrous colloidal silicon: ............................... 7 mg Butylhydroxytoluene ....................................... 0,3 mg Gelatin q.s. to .............................................. 390 mg Indication: Rheumatology: Symptomatic slow-acting treatment of osteoarthritis of hip and knee.Dentistry: Adjunctive treatment of periodontitis. Dosage: 1 capsule once daily with a meal. Take the capsule with abundant water. Contraindication: History of hypersensitivity to any of the components in the formula. Pregnancy and breastfeeding: There is no available data to evaluate teratogenic or fetotoxic effects. Therefore, it should not be used during pregnancy and breastfeeding. Drug interactions: Severe interactions were not reported. Nevertheless, to avoid interactions with other drugs, the patient shall inform the physician if she/he is taking another medicine. Adverse reactions: Infrequent: In some patients, it may cause lipid-scented regurgitations. To avoid this discomfort, capsules should be taken with meals. Rare: Hypersensitivity. Extremely rare: liver disorders, including increased transaminases, alkaline phosphatases, bilirubin and gamma-glutamyl transpeptidase. Unknown frequency: gastrointestinal disorders, such as: diarrhea and epigastric pain.
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