Nature's Bounty Turmeric Capsules, 450 Mg | Herbal Supplement with Plant-Based Antioxidants

Great product and works well. The polyphenols in this spice increases your BDNF levels, that is why I bought it. I have noticed a difference in my performance and emotional response.

I have been taking Turmeric for months to help with chronic pain, and I think it is a very useful addition to my pain management routine. This brand also does NOT contain black pepper/bioperine, which was what I was looking for. Black pepper may be good sometimes for some people, but there is good evidence showing that it increases blood serum levels of other medications, including beta blockers (taken to control blood pressure and heart rate, and some of the most commonly prescribed medications), which I take. Blood serum levels dictate how much of the dose you are taking actually gets to the site of action-- the thing in your body the medication has some influence upon-- so an unintended increase in blood serum levels of your heart medication isn't good. It may have some independent benefits and increase the turmeric absorption, but it also increases the absorption of other medications which can have dangerous side effects. Here is a list of medications on which black pepper/bioperine/piperine increases the bioavailability: barbiturates beta-carotene coenzyme Q10 (CoQ10) curcumin (extract from turmeric) dapsone ethambutol isoniazid nalorphine phenytoin propranolol pyrazinamide rifampicin selenium (from selenomethionine) sulfadiazene theophylline vitamin B-6 (pyridoxine) glucose (absorption increased) amino acids (absorption increased) Turmeric is on the list, which is why adding it to turmeric/curcumin supplements makes them more effective. It is a problem when it works the same way on other medications that have more sensitive dosing (your doctor has chosen the dose he or she wants you on for a reason!). Increasing the bioavailability-- which is essentially increasing the dose-- of things like barbiturates, seizure medications, and blood pressure and heart rate lowering drugs can be very, very dangerous. You can find more information in an article here: http://www.delano.com/blog/?p=70 Metabolizing enzymes inhibited or induced by piperine, and a few of the substances whose bioavailability is affected by these enzymes Metabolizing Enzymes: CYP1A1, CYP1B1, CYP1B2, CYP2E1, CYP3A4 Drugs: acetaminophen, alfentanyl, amiodarone, amlodipine, astemizole, atorvastatin, barbiturates, benzodiazepines, buspirone, Cafergot, caffeine, carbamazepine, cerivastatin, chlorpheniramine, chlorzoxazone, cimetidine, ciprofloxacin, cisapride, clarithromycin, cocaine, codeine, cyclosporine, dapsone, dextromethorphan, diethyl-dithiocarbamate, diltiazem, disulfiram, efavirenz, enflurane, eplerenone, erythromycin, estradiol, ethanol, felodipine, fentanyl, finasteride, fluconazole, fluvoxamine, gestodene, Gleevec, glucocorticoids, haloperidol, halothane, hydrocortisone, indinavir, irinotecan, isoflurane, isoniazid, itraconazole, ketoconazole, LAAM, lercanidipine, lidocaine, lovastatin, methadone, methoxyflurane, mibefradil, mifepristone, modafinil, nefazodone, nelfinavir, nevirapine, nifedipine, nisoldipine, nitrendipine, norfloxacin, norfluoxetine, odanestron, phenobarbital, phenytoin, pimozide, pioglitazone, progesterone, propranolol, quinidine, quinine, rifabutin, rifampin, ritonavir, salmeterol, saquinavir, sevoflurane, sildenafil (Viagra), simvastatin, sirolimus, St. John’s wort, tamoxifen, taxol, terfenadine, testosterone, theophylline, trazodone, troglitazone, verapamil, vincristine, zaleplon, zolpidem Turmeric has been used for thousands of years for its medicinal properties, and is one of the few "alternative" remedies that has empirical evidence supporting its efficacy as an anti inflammatory. It can be used in place of or as an adjunct to modern medicine to treat pain. Less well studied for turmeric uses include immune system support and digestive healthcare (sort of like a pro-biotic). I've really found that it helps my joint pain and that's all I can speak to. Overall I highly recommend that anyone with regular or chronic pain try turmeric as an alternative to NSAIDS (Tylenol, Advil, ibuprofen, etc.) or as a supplement to those and other pain treatments. I find that it makes my pain medication more effective without increasing or causing new side effects, and that is really a hard thing to find. If you take ANY prescription medication or supplements that are dose dependent it is better to stay away from the black pepper/piperine/bioperine (they are all forms of the same thing), and that really includes things like tylenol. Since this is one of the few brands of turmeric that does not contain black pepper, it’s a good choice in my opinion.

I was looking for a quality turmeric supplement from a brand I already trust, and this one fit what I needed. One important factor for me was that it uses bovine gelatin instead of pork, which is why I chose it. Smells like real turmeric.

Turmeric is know to be great at helping the body fight inflammation. Rather than use costly pharmaceuticals with sometimes DANGEROUS side effects try this first. My story may not include scientific results, but I have suffered from years of inflammation and pain and gone thru many prescriptions of Opiates (including Vicodin, Dilaudid, Oxycodone, Hydrocodone. Morphine) for pain and antiinflammatories like Celebrex (which I stopped taking after reading the insert with the product). I have had 7 major orthopedic operations as a result of a car accident 5 years ago and am still in need of 3 operations including a knee replacement. Besides that I suffer from headaches and back pain. Preceding my taking of turmeric I was taking on average 7-10 pain killers weekly (10 mg opioid) for severe pain. While the pain is chronic I refuse to suffer thru a third detox from opiates. Two were when stopping morphine after 6-12 months of usage (never using more than prescribed) the final was when stopping my daily use of oxycodone after two operations 6 weeks apart. Therefore I limited my pill intake. While I am not 100% pain free, due to severely damaged knees and having a shattered femur repaired with a rod, plus the removal of 1/3 of my right fibula, I am able to walk pain free many days and even rarely use a cane anymore. I have taken just a single pain killer in the previous 3 weeks. All of these improvements occurred several weeks after taking this product daily. I did also make improvements to my diet at the same time. The improvement in my quality of life and mobility is indescribable. Its worth the money to try it for yourself and see if it helps.

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